Six Degrees of Separation is a play (early 90's) written by John Guare, which ruminates the idea that any two individual are connected by at most five others. This piece is noted to popularize the phrase "six degrees of separation" although the idea of which have been circulating for decades in many forms.
John Guare's play was already a success which already created million, maybe billion and also has a film adaptation in 1993.
There are upcoming play revivals for this piece this year to be held at the Old Globe Theatre. More details can be read on the link below
Link: Review: 'Six Degrees of Separation' at Old Globe Theatre | Culture Monster | Los Angeles Times